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Descriptor English: Cross-Linking Reagents
Descriptor Spanish: Reactivos de Enlaces Cruzados
Descriptor reactivos de enlaces cruzados
Entry term(s) reactivos bifuncionales
reactivos de uniones cruzadas
Scope note: Reactivos con dos grupos reactivos, que generalmente se encuentran en extremos opuestos de la molécula, que son capaces de reaccionar y así formar puentes entre las cadenas laterales de los aminoácidos de las proteínas. Las ubicaciones de las áreas naturalmente reactivas de las proteínas pueden identificarse de esta forma; también pueden utilizarse con otras macromoléculas, como glicoproteínas, ácidos nucleicos, etcétera.
Descriptor Portuguese: Reagentes de Ligações Cruzadas
Descriptor French: Réactifs réticulants
Entry term(s): Bifunctional Reagent
Bifunctional Reagents
Cross Linking Reagent
Cross Linking Reagents
Crosslinking Reagent
Crosslinking Reagents
Linking Reagents, Cross
Reagents, Bifunctional
Reagents, Cross Linking
Reagents, Cross-Linking
Reagents, Crosslinking
Tree number(s): D27.720.470.410.210
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D003432
Scope note: Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
Previous Indexing: Indicators and Reagents (1966-1979)
Protein Binding (1966-1979)
Public MeSH Note: 80
History Note: 80
DeCS ID: 3447
Unique ID: D003432
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1980/01/01
Date of Entry: 1979/03/01
Revision Date: 2003/07/09
Cross-Linking Reagents - Preferred
Concept UI M0005349
Scope note Reagents with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between side chains of amino acids in proteins; the locations of naturally reactive areas within proteins can thereby be identified; may also be used for other macromolecules, like glycoproteins, nucleic acids, or other.
Preferred term Cross-Linking Reagents
Entry term(s) Bifunctional Reagent
Bifunctional Reagents
Cross Linking Reagent
Cross Linking Reagents
Crosslinking Reagent
Crosslinking Reagents
Linking Reagents, Cross
Reagents, Bifunctional
Reagents, Cross Linking
Reagents, Cross-Linking
Reagents, Crosslinking



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